The "Don't Do X, Worst Mistake of My Life" meme format typically features a cautionary or satirical warning about engaging in specific actions or visiting certain locations. The template prominently includes an image of Peter Griffin from the animated show Family Guy, portrayed in a state of frantic retreat. This is visually reminiscent of the meme cohort known as Doge in Danger, which similarly depict warnings or danger cues.
The meme traces its origin back to the "North by North Quahog" episode of Family Guy, which first aired on May 1, 2005. This episode includes a sequence where Peter Griffin comically flees from an aggressive crop duster, a scene that parodies a similar moment in the 1959 film North by Northwest. The relevant clip can be viewed on YouTube. The meme format itself gained popularity on October 27, 2018, when a Reddit user named J-Dad began using the image of the fleeing Peter Griffin in various advice or warning themed image macros within the subreddit /r/okbuddyretard, marking the start of its spread throughout internet culture.[1]
Origin: 2018